Disease: Large cell neuroendocrine carcinoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ENO2 P09104 enolase 2 Enzyme 0.38 0.475 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
KITLG P21583 KIT ligand 0.85 0.473 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
KRT5 P13647 keratin 5 0.64 0.512 0.731
NKX2-1 P43699 NK2 homeobox 1 Transcription factor 0.36 0.457 0.808
PEBP1 P30086 phosphatidylethanolamine binding protein 1 Enzyme modulator 9.2E-02 0.500 0.808
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
SCLC1 small cell cancer of the lung 0.612 0.577
STMN1 P16949 stathmin 1 7.5E-02 0.458 0.885
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
TTF1 Q15361 transcription termination factor 1 6.2E-13 0.537 0.500
UBE2C O00762 ubiquitin conjugating enzyme E2 C 0.11 0.558 0.615
UVRAG Q9P2Y5 UV radiation resistance associated 0.99 0.436 0.769