Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
IL2 | P60568 | interleukin 2 | 0.48 | 0.336 | 0.885 | |
ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
FAS | P25445 | Fas cell surface death receptor | 0.81 | 0.372 | 0.923 | |
FN1 | P02751 | fibronectin 1 | Signaling | 1.4E-03 | 0.365 | 0.962 |
REN | P00797 | renin | Enzyme | 2.4E-07 | 0.370 | 0.923 |
CD34 | P28906 | CD34 molecule | 5.0E-06 | 0.368 | 0.808 | |
HGF | P14210 | hepatocyte growth factor | Enzyme | 1.00 | 0.374 | 0.885 |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
VIM | P08670 | vimentin | 0.71 | 0.372 | 0.846 | |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | |
TWIST1 | Q15672 | twist family bHLH transcription factor 1 | Transcription factor | 0.34 | 0.397 | 0.846 |
SOX2 | P48431 | SRY-box transcription factor 2 | Transcription factor | 0.71 | 0.405 | 0.808 |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |
SMARCB1 | Q12824 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | Nucleic acid binding | 1.00 | 0.434 | 0.846 |