Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
H3P10 H3 histone pseudogene 10 0.350 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
UVRAG Q9P2Y5 UV radiation resistance associated 0.99 0.436 0.769
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
NKX2-1 P43699 NK2 homeobox 1 Transcription factor 0.36 0.457 0.808