Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
CD44 | P16070 | CD44 molecule (Indian blood group) | 2.4E-07 | 0.363 | 0.962 | |
SLC2A1 | P11166 | solute carrier family 2 member 1 | Transporter | 0.99 | 0.388 | 0.808 |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
PCNA | P12004 | proliferating cell nuclear antigen | Nucleic acid binding | 0.98 | 0.382 | 0.846 |
LGALS3 | P17931 | galectin 3 | Signaling | 2.3E-05 | 0.392 | 0.846 |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
WT1 | P19544 | WT1 transcription factor | Nucleic acid binding | 1.00 | 0.422 | 0.808 |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |
HMGA2 | P52926 | high mobility group AT-hook 2 | Nucleic acid binding | 0.87 | 0.429 | 0.808 |
MEN1 | O00255 | menin 1 | 1.00 | 0.444 | 0.808 | |
MKI67 | P46013 | marker of proliferation Ki-67 | 1.3E-28 | 0.431 | 0.808 | |
MED12 | Q93074 | mediator complex subunit 12 | Transcription factor | 1.00 | 0.476 | 0.769 |
DES | P17661 | desmin | 8.8E-03 | 0.460 | 0.846 | |
MIB1 | Q86YT6 | mindbomb E3 ubiquitin protein ligase 1 | Enzyme | 3.4E-88 | 0.438 | 0.769 |
APEX1 | P27695 | apurinic/apyrimidinic endodeoxyribonuclease 1 | 1.9E-07 | 0.458 | 0.846 |