Disease: Islet Cell Tumor
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
SST P61278 somatostatin Signaling 0.34 0.399 0.885
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846
STMN1 P16949 stathmin 1 7.5E-02 0.458 0.885
KRT19 P08727 keratin 19 4.3E-03 0.460 0.731
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
CHGA P10645 chromogranin A 3.0E-02 0.490 0.808
ELK3 P41970 ETS transcription factor ELK3 Transcription factor 8.4E-02 0.490 0.846
FGFR4 P22455 fibroblast growth factor receptor 4 Kinase 7.2E-13 0.490 0.769
SLC6A2 P23975 solute carrier family 6 member 2 Transporter 8.2E-02 0.490 0.846
EPHB1 P54762 EPH receptor B1 Kinase 1.00 0.518 0.846