Disease: Childhood Medulloblastoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
PSIP1 O75475 PC4 and SFRS1 interacting protein 1 Signaling 1.00 0.490 0.846
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PHF5A Q7RTV0 PHD finger protein 5A 0.87 0.686 0.308
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
PAWR Q96IZ0 pro-apoptotic WT1 regulator 9.0E-02 0.542 0.846
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NEUROG1 Q92886 neurogenin 1 Enzyme 2.2E-04 0.656 0.538
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MARCKSL1 P49006 MARCKS like 1 1.4E-02 0.508 0.731
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
MAP2 P11137 microtubule associated protein 2 1.00 0.537 0.692
LIF P15018 LIF interleukin 6 family cytokine Signaling 0.52 0.483 0.769
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808