Disease: Hereditary Nonpolyposis Colorectal Cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BAAT Q14032 bile acid-CoA:amino acid N-acyltransferase 7.9E-08 0.578 0.654
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
DNMT3B Q9UBC3 DNA methyltransferase 3 beta 0.20 0.453 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
H3P10 H3 histone pseudogene 10 0.350 0.846
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962