Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
ASS1 | P00966 | argininosuccinate synthase 1 | Enzyme | 1.5E-09 | 0.523 | 0.731 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CLDN4 | O14493 | claudin 4 | Cell-cell junction | 7.0E-05 | 0.514 | 0.692 |
CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
CTLA4 | P16410 | cytotoxic T-lymphocyte associated protein 4 | 0.94 | 0.369 | 0.923 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
ELK3 | P41970 | ETS transcription factor ELK3 | Transcription factor | 8.4E-02 | 0.490 | 0.846 |
ENO2 | P09104 | enolase 2 | Enzyme | 0.38 | 0.475 | 0.846 |
EPHB1 | P54762 | EPH receptor B1 | Kinase | 1.00 | 0.518 | 0.846 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
GPC3 | P51654 | glypican 3 | 1.00 | 0.466 | 0.808 | |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
IGF2BP3 | O00425 | insulin like growth factor 2 mRNA binding protein 3 | Enzyme | 1.00 | 0.570 | 0.577 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |