Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CCNE1 P24864 cyclin E1 Enzyme modulator 0.97 0.538 0.731
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CLDN3 O15551 claudin 3 Cell-cell junction 0.52 0.558 0.615
CLDN4 O14493 claudin 4 Cell-cell junction 7.0E-05 0.514 0.692
DCTN6 O00399 dynactin subunit 6 Cellular structure 5.6E-02 0.442 0.769
EEC1 ectrodactyly, ectodermal dysplasia and cleft lip/palate syndrome 1 0.691 0.538
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FBXW7 Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 1.00 0.465 0.808
H3P10 H3 histone pseudogene 10 0.350 0.846
H3P23 H3 histone pseudogene 23 0.443 0.769
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
MSLN Q13421 mesothelin Extracellular structure 5.9E-25 0.525 0.692
MUC16 Q8WXI7 mucin 16, cell surface associated 8.3E-112 0.479 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PPP2R1A P30153 protein phosphatase 2 scaffold subunit Aalpha Enzyme 0.98 0.588 0.577
PSMD9 O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 4.9E-06 0.435 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923