Disease: Large cell neuroendocrine carcinoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ASCL1 P50553 achaete-scute family bHLH transcription factor 1 Transcription factor 0.68 0.552 0.692
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CHGA P10645 chromogranin A 3.0E-02 0.490 0.808
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DLL3 Q9NYJ7 delta like canonical Notch ligand 3 5.4E-05 0.552 0.654
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ELK3 P41970 ETS transcription factor ELK3 Transcription factor 8.4E-02 0.490 0.846
ENO2 P09104 enolase 2 Enzyme 0.38 0.475 0.846
EPHB1 P54762 EPH receptor B1 Kinase 1.00 0.518 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846
H3P10 H3 histone pseudogene 10 0.350 0.846
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
INSM1 Q01101 INSM transcriptional repressor 1 0.27 0.584 0.654
ISL1 P61371 ISL LIM homeobox 1 Transcription factor 0.87 0.579 0.654
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808