Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
HLA-B | P01889 | major histocompatibility complex, class I, B | 3.9E-05 | 0.379 | 0.885 | |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
CASP8 | Q14790 | caspase 8 | Enzyme | 3.7E-06 | 0.404 | 0.923 |
RAC1 | P63000 | Rac family small GTPase 1 | Enzyme modulator | 0.76 | 0.429 | 0.962 |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
FOXP1 | Q9H334 | forkhead box P1 | 1.00 | 0.460 | 0.808 | |
CYP1B1 | Q16678 | cytochrome P450 family 1 subfamily B member 1 | Enzyme | 2.2E-05 | 0.457 | 0.769 |
TYR | P14679 | tyrosinase | Enzyme | 5.0E-32 | 0.473 | 0.808 |
TRPS1 | Q9UHF7 | transcriptional repressor GATA binding 1 | 1.00 | 0.537 | 0.769 | |
CDKN2B-AS1 | CDKN2B antisense RNA 1 | 0.491 | 0.769 | |||
KRT5 | P13647 | keratin 5 | 0.64 | 0.512 | 0.731 | |
IRF4 | Q15306 | interferon regulatory factor 4 | Transcription factor | 0.86 | 0.491 | 0.769 |
GPX4 | P36969 | glutathione peroxidase 4 | Enzyme | 4.8E-05 | 0.516 | 0.808 |
MC1R | Q01726 | melanocortin 1 receptor | G-protein coupled receptor | 8.1E-11 | 0.524 | 0.808 |
HERC2 | O95714 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | 1.00 | 0.568 | 0.692 | |
LPP | Q93052 | LIM domain containing preferred translocation partner in lipoma | Enzyme modulator | 7.2E-03 | 0.543 | 0.769 |
CTSS | P25774 | cathepsin S | Enzyme | 0.34 | 0.539 | 0.731 |
BACH2 | Q9BYV9 | BTB domain and CNC homolog 2 | 1.00 | 0.539 | 0.731 | |
EFEMP2 | O95967 | EGF containing fibulin extracellular matrix protein 2 | Calcium-binding protein | 8.2E-03 | 0.559 | 0.692 |
CLPTM1L | Q96KA5 | CLPTM1 like | Enzyme | 4.4E-05 | 0.551 | 0.654 |
PPARGC1B | Q86YN6 | PPARG coactivator 1 beta | Transcription factor | 0.50 | 0.569 | 0.731 |