Disease: Cytogenetically normal acute myeloid leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
MIR34A microRNA 34a 0.421 0.846
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
CEBPA P49715 CCAAT enhancer binding protein alpha Transcription factor 0.55 0.496 0.692
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
GAS6 Q14393 growth arrest specific 6 Extracellular structure 3.4E-02 0.500 0.769