Disease: Sarcoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PRKDC P78527 protein kinase, DNA-activated, catalytic subunit Kinase 1.00 0.540 0.808
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TRIO O75962 trio Rho guanine nucleotide exchange factor Kinase 1.00 0.556 0.731
HDAC4 P56524 histone deacetylase 4 Epigenetic regulator 1.00 0.484 0.885
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
ATN1 P54259 atrophin 1 1.00 0.409 0.885
LATS1 O95835 large tumor suppressor kinase 1 Kinase 1.00 0.563 0.731
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
HDAC9 Q9UKV0 histone deacetylase 9 Epigenetic regulator 1.00 0.439 0.846
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
FBXW7 Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 1.00 0.465 0.808
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
ZNF654 Q8IZM8 zinc finger protein 654 Enzyme 1.00 0.582 0.500
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808