Disease: Thrombocythemia, Essential
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
FIP1L1 Q6UN15 factor interacting with PAPOLA and CPSF1 0.79 0.575 0.577
IFNA1 P01562 interferon alpha 1 0.371 0.923
IFNA13 P01562 interferon alpha 13 0.374 0.923
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
IL6 P05231 interleukin 6 0.32 0.248 0.962
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577