Disease: Childhood Acute Myeloid Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CBFB Q13951 core-binding factor subunit beta 0.96 0.601 0.538
CD33 P20138 CD33 molecule Receptor 5.7E-07 0.524 0.769
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885
CEBPZ Q03701 CCAAT enhancer binding protein zeta Transcription factor 6.5E-06 0.595 0.692
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
IL3RA P26951 interleukin 3 receptor subunit alpha Signaling 3.0E-27 0.560 0.769
IL6 P05231 interleukin 6 0.32 0.248 0.962
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
U2AF1L5 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 like 5 0.769 0.308