Disease: Flexion contracture of proximal interphalangeal joint
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846
GPC3 P51654 glypican 3 1.00 0.466 0.808
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808
IKBKG Q9Y6K9 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Kinase 8.5E-02 0.493 0.769
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692
NOG Q13253 noggin 0.89 0.518 0.731
SUZ12 Q15022 SUZ12 polycomb repressive complex 2 subunit Nucleic acid binding 1.00 0.529 0.577
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
NAA10 P41227 N-alpha-acetyltransferase 10, NatA catalytic subunit Enzyme 0.76 0.535 0.692
DVL3 Q92997 dishevelled segment polarity protein 3 Signaling 0.39 0.537 0.731
FAT4 Q6V0I7 FAT atypical cadherin 4 1.00 0.539 0.808
PORCN Q9H237 porcupine O-acyltransferase Enzyme 1.00 0.545 0.692
GPC4 O75487 glypican 4 0.93 0.547 0.769
DLL3 Q9NYJ7 delta like canonical Notch ligand 3 5.4E-05 0.552 0.654
FZD2 Q14332 frizzled class receptor 2 G-protein coupled receptor 0.65 0.558 0.654