Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
HLA-DRB1 | P01911 | major histocompatibility complex, class II, DR beta 1 | Immune response | 1.1E-03 | 0.333 | 0.923 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
DMD | P11532 | dystrophin | 1.00 | 0.423 | 0.923 | |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
TTN | Q8WZ42 | titin | Kinase | 2.6E-96 | 0.470 | 0.885 |
SDHD | O14521 | succinate dehydrogenase complex subunit D | Transporter | 0.34 | 0.472 | 0.885 |
MFN2 | O95140 | mitofusin 2 | Enzyme | 0.99 | 0.471 | 0.846 |
RYR1 | P21817 | ryanodine receptor 1 | Ion channel | 1.6E-29 | 0.489 | 0.808 |
SMN1 | Q16637 | survival of motor neuron 1, telomeric | Epigenetic regulator | 1.6E-02 | 0.454 | 0.769 |
SDHB | P21912 | succinate dehydrogenase complex iron sulfur subunit B | Enzyme | 2.4E-04 | 0.474 | 0.846 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
SMN2 | Q16637 | survival of motor neuron 2, centromeric | 0.10 | 0.459 | 0.769 | |
TPM3 | P06753 | tropomyosin 3 | Cellular structure | 6.7E-03 | 0.490 | 0.808 |
SNAP25 | P60880 | synaptosome associated protein 25 | Transporter | 0.99 | 0.489 | 0.808 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
MYH7 | P12883 | myosin heavy chain 7 | 4.2E-16 | 0.516 | 0.692 | |
FKRP | Q9H9S5 | fukutin related protein | 9.8E-06 | 0.513 | 0.731 | |
STIM1 | Q13586 | stromal interaction molecule 1 | 0.78 | 0.501 | 0.808 | |
SDHA | P31040 | succinate dehydrogenase complex flavoprotein subunit A | Enzyme | 2.6E-10 | 0.517 | 0.731 |
TWNK | Q96RR1 | twinkle mtDNA helicase | Enzyme | 3.2E-03 | 0.516 | 0.692 |
TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
SYNE1 | Q8NF91 | spectrin repeat containing nuclear envelope protein 1 | 3.2E-52 | 0.511 | 0.846 | |
CHAT | P28329 | choline O-acetyltransferase | Enzyme | 5.6E-11 | 0.520 | 0.808 |