Disease: Pulmonary Emphysema
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AMFR Q9UKV5 autocrine motility factor receptor 5.8E-05 0.599 0.692
ATD asphixiating thoracic dystrophy (chondroectodermal dysplasia-like syndrome) 0.656 0.731
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CELA1 Q9UNI1 chymotrypsin like elastase 1 Enzyme 2.4E-04 0.700 0.385
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692
COPD Pulmonary disease, chronic obstructive, severe early-onset 0.456 0.885
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
ELANE P08246 elastase, neutrophil expressed Enzyme 1.2E-03 0.447 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
FEV Q99581 FEV transcription factor, ETS family member Transcription factor 8.1E-03 0.593 0.692
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
KLF10 Q13118 Kruppel like factor 10 Nucleic acid binding 4.6E-03 0.631 0.615
KLF9 Q13886 Kruppel like factor 9 Nucleic acid binding 0.89 0.595 0.577
MMP12 P39900 matrix metallopeptidase 12 Enzyme 0.484 0.885
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MSC O60682 musculin 2.5E-02 0.475 0.846
PLF Pulmonary function 0.544 0.731
PRTN3 P24158 proteinase 3 Enzyme 3.8E-05 0.503 0.808
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
SERPINA13P Q6UXR4 serpin family A member 13, pseudogene 0.619 0.692
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846