Disease: Mitochondrial Myopathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CAV3 P56539 caveolin 3 Enzyme modulator 5.5E-03 0.564 0.692
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
COX3 P00414 cytochrome c oxidase III Enzyme 0.546 0.808
CPOX P36551 coproporphyrinogen oxidase Enzyme 0.17 0.488 0.846
DGUOK Q16854 deoxyguanosine kinase Kinase 3.7E-07 0.593 0.500
DNA2 P51530 DNA replication helicase/nuclease 2 1.3E-18 0.626 0.731
FDX2 Q6P4F2 ferredoxin 2 1.7E-03 0.780 0.346
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
MSTO1 Q9BUK6 misato mitochondrial distribution and morphology regulator 1 1.6E-09 0.582 0.692
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
POLG2 Q9UHN1 DNA polymerase gamma 2, accessory subunit Enzyme 1.5E-10 0.558 0.769
RRM2B Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 2.4E-03 0.527 0.769
SLC25A4 P12235 solute carrier family 25 member 4 Transporter 0.45 0.568 0.692
TK2 O00142 thymidine kinase 2 Kinase 3.9E-07 0.585 0.615
TMEM126B Q8IUX1 transmembrane protein 126B 1.9E-04 0.716 0.385
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962