Disease: Acidosis, Lactic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATAD3A Q9NVI7 ATPase family AAA domain containing 3A Enzyme 4.1E-09 0.628 0.692
ATP5F1D P30049 ATP synthase F1 subunit delta Transporter 7.4E-02 0.674 0.500
COQ9 O75208 coenzyme Q9 5.5E-06 0.700 0.423
DLD P09622 dihydrolipoamide dehydrogenase Enzyme 9.5E-03 0.517 0.769
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
EXOSC9 Q06265 exosome component 9 Enzyme 1.8E-11 0.705 0.423
FARS2 O95363 phenylalanyl-tRNA synthetase 2, mitochondrial Enzyme 9.3E-09 0.615 0.731
FBXL4 Q9UKA2 F-box and leucine rich repeat protein 4 1.1E-08 0.695 0.423
FOXRED1 Q96CU9 FAD dependent oxidoreductase domain containing 1 Enzyme 2.0E-16 0.633 0.462
GTPBP3 Q969Y2 GTP binding protein 3, mitochondrial 4.2E-09 0.805 0.154
HADHA P40939 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Enzyme 4.4E-06 0.569 0.769
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
LIAS O43766 lipoic acid synthetase 2.3E-05 0.695 0.538
LIPT2 A6NK58 lipoyl(octanoyl) transferase 2 0.63 0.821 0.154
LYRM4 Q9HD34 LYR motif containing 4 0.20 0.736 0.385
MICOS13 Q5XKP0 mitochondrial contact site and cristae organizing system subunit 13 8.3E-04 0.736 0.346
MIPEP Q99797 mitochondrial intermediate peptidase Enzyme 1.6E-15 0.666 0.615
MRPS34 P82930 mitochondrial ribosomal protein S34 2.6E-03 0.722 0.346
MTO1 Q9Y2Z2 mitochondrial tRNA translation optimization 1 7.4E-06 0.670 0.462
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ND2 P03891 MTND2 0.601 0.615
ND3 P03897 NADH dehydrogenase, subunit 3 (complex I) 0.604 0.654
NDUFA1 O15239 NADH:ubiquinone oxidoreductase subunit A1 0.55 0.636 0.423
NDUFA11 Q86Y39 NADH:ubiquinone oxidoreductase subunit A11 1.8E-02 0.705 0.308
NDUFA6 P56556 NADH:ubiquinone oxidoreductase subunit A6 Enzyme 1.3E-04 0.711 0.346