Disease: PARKINSON DISEASE, LATE-ONSET
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
MSMB P08118 microseminoprotein beta Signaling 1.6E-02 0.498 0.846
NR4A2 P43354 nuclear receptor subfamily 4 group A member 2 Nuclear receptor 1.00 0.529 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
TBP P20226 TATA-box binding protein Transcription factor 1.5E-02 0.552 0.846
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
EEF1A2 Q05639 eukaryotic translation elongation factor 1 alpha 2 Enzyme 1.00 0.554 0.808
EIF4G1 Q04637 eukaryotic translation initiation factor 4 gamma 1 Nucleic acid binding 1.00 0.553 0.808
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
ATXN3 P54252 ataxin 3 Enzyme 0.11 0.521 0.808
PSPH P78330 phosphoserine phosphatase Enzyme 9.7E-04 0.570 0.808
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
PARK7 Q99497 Parkinsonism associated deglycase Enzyme 0.75 0.535 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
BPIFA2 Q96DR5 BPI fold containing family A member 2 8.0E-07 0.608 0.808
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808