Disease: Muscle Rigidity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
DHDDS Q86SQ9 dehydrodolichyl diphosphate synthase subunit Enzyme 0.25 0.468 0.885
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
PAFAH1B1 P43034 platelet activating factor acetylhydrolase 1b regulatory subunit 1 1.00 0.504 0.769
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731