Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
SOD2 | P04179 | superoxide dismutase 2 | Enzyme | 0.15 | 0.379 | 0.923 |
PDGFRB | P09619 | platelet derived growth factor receptor beta | Kinase | 0.90 | 0.416 | 0.846 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
DRD2 | P14416 | dopamine receptor D2 | G-protein coupled receptor | 0.75 | 0.436 | 0.846 |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
NQO1 | P15559 | NAD(P)H quinone dehydrogenase 1 | 1.2E-09 | 0.434 | 0.885 | |
TET2 | Q6N021 | tet methylcytosine dioxygenase 2 | 4.3E-54 | 0.458 | 0.808 | |
CSF1R | P07333 | colony stimulating factor 1 receptor | Kinase | 0.13 | 0.448 | 0.808 |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
FMR1 | Q06787 | FMRP translational regulator 1 | Nucleic acid binding | 0.65 | 0.473 | 0.769 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
TH | P07101 | tyrosine hydroxylase | 1.7E-06 | 0.462 | 0.885 | |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
DHDDS | Q86SQ9 | dehydrodolichyl diphosphate synthase subunit | Enzyme | 0.25 | 0.468 | 0.885 |
PDGFB | P01127 | platelet derived growth factor subunit B | Signaling | 0.77 | 0.488 | 0.846 |
TPM3 | P06753 | tropomyosin 3 | Cellular structure | 6.7E-03 | 0.490 | 0.808 |
ASXL1 | Q8IXJ9 | ASXL transcriptional regulator 1 | 1.3E-14 | 0.482 | 0.808 | |
NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
SCN1A | P35498 | sodium voltage-gated channel alpha subunit 1 | Ion channel | 1.00 | 0.477 | 0.808 |