Disease: Presenile dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KCNIP3 Q9Y2W7 potassium voltage-gated channel interacting protein 3 Ion channel 3.8E-02 0.626 0.654
ITM2B Q9Y287 integral membrane protein 2B 0.63 0.617 0.654
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
PYCARD Q9ULZ3 PYD and CARD domain containing Enzyme 2.0E-04 0.457 0.808
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
SLC17A7 Q9P2U7 solute carrier family 17 member 7 Transporter 1.00 0.636 0.308
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
SLC17A5 Q9NRA2 solute carrier family 17 member 5 Transporter 6.9E-10 0.491 0.808
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
TXNIP Q9H3M7 thioredoxin interacting protein 0.16 0.490 0.731
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
HDAC2 Q92769 histone deacetylase 2 Epigenetic regulator 1.00 0.476 0.846
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
NRGN Q92686 neurogranin 0.48 0.608 0.615