Disease: Presenile dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
ADA P00813 adenosine deaminase Enzyme 2.9E-12 0.440 0.885
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885
SMPD1 P17405 sphingomyelin phosphodiesterase 1 Enzyme 3.9E-10 0.499 0.885
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846
SLC17A5 Q9NRA2 solute carrier family 17 member 5 Transporter 6.9E-10 0.491 0.808
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
FOLH1 Q04609 folate hydrolase 1 Enzyme 6.2E-09 0.453 0.885
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808
NAGLU P54802 N-acetyl-alpha-glucosaminidase 1.4E-08 0.546 0.769
PAEP P09466 progestagen associated endometrial protein Enzyme 3.1E-08 0.430 0.846
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
REM1 O75628 RRAD and GEM like GTPase 1 5.3E-08 0.531 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923