Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
ARSA | P15289 | arylsulfatase A | Enzyme | 1.1E-11 | 0.448 | 0.923 |
TTN | Q8WZ42 | titin | Kinase | 2.6E-96 | 0.470 | 0.885 |
RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
NKX2-1 | P43699 | NK2 homeobox 1 | Transcription factor | 0.36 | 0.457 | 0.808 |
SCN8A | Q9UQD0 | sodium voltage-gated channel alpha subunit 8 | Ion channel | 1.00 | 0.510 | 0.731 |
TPM3 | P06753 | tropomyosin 3 | Cellular structure | 6.7E-03 | 0.490 | 0.808 |
SCO2 | O43819 | synthesis of cytochrome C oxidase 2 | Enzyme | 7.5E-07 | 0.479 | 0.846 |
DCC | P43146 | DCC netrin 1 receptor | 0.99 | 0.471 | 0.808 | |
SLC52A2 | Q9HAB3 | solute carrier family 52 member 2 | Transporter | 2.5E-03 | 0.483 | 0.808 |
GRIN2B | Q13224 | glutamate ionotropic receptor NMDA type subunit 2B | Ion channel | 1.00 | 0.510 | 0.692 |
TWNK | Q96RR1 | twinkle mtDNA helicase | Enzyme | 3.2E-03 | 0.516 | 0.692 |
TPM2 | P07951 | tropomyosin 2 | Cellular structure | 2.4E-04 | 0.530 | 0.654 |
GJB1 | P08034 | gap junction protein beta 1 | Cell-cell junction | 0.85 | 0.514 | 0.731 |
POLR3A | O14802 | RNA polymerase III subunit A | Enzyme | 1.3E-23 | 0.538 | 0.769 |
ACTA1 | P68133 | actin alpha 1, skeletal muscle | Cellular structure | 1.1E-06 | 0.540 | 0.769 |
NTN1 | O95631 | netrin 1 | Enzyme modulator | 1.00 | 0.509 | 0.846 |
ATXN3 | P54252 | ataxin 3 | Enzyme | 0.11 | 0.521 | 0.808 |
KMT2B | Q9UMN6 | lysine methyltransferase 2B | 1.00 | 0.529 | 0.808 | |
PSAP | P07602 | prosaposin | 0.99 | 0.532 | 0.846 | |
ATP7B | P35670 | ATPase copper transporting beta | Transporter | 4.8E-30 | 0.529 | 0.654 |
PANK2 | Q9BZ23 | pantothenate kinase 2 | Kinase | 7.4E-07 | 0.559 | 0.808 |
CAV3 | P56539 | caveolin 3 | Enzyme modulator | 5.5E-03 | 0.564 | 0.692 |