Disease: Ataxia, Spinocerebellar
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATXN10 Q9UBB4 ataxin 10 3.5E-04 0.650 0.385
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
ATXN3 P54252 ataxin 3 Enzyme 0.11 0.521 0.808
ATXN7 O15265 ataxin 7 0.96 0.581 0.654
ATXN8OS P0DMR3 ATXN8 opposite strand lncRNA 0.650 0.423
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
COQ2 Q96H96 coenzyme Q2, polyprenyltransferase Enzyme 1.3E-03 0.590 0.731
COQ8A Q8NI60 coenzyme Q8A Kinase 9.3E-11 0.674 0.385
ELOVL4 Q9GZR5 ELOVL fatty acid elongase 4 Enzyme 0.83 0.601 0.577
GRM1 Q13255 glutamate metabotropic receptor 1 G-protein coupled receptor 0.14 0.528 0.808
HTT P42858 huntingtin 1.00 0.548 0.654
ITPR1 Q14643 inositol 1,4,5-trisphosphate receptor type 1 Ion channel 1.00 0.534 0.846
KCNC3 Q14003 potassium voltage-gated channel subfamily C member 3 Ion channel 0.21 0.705 0.462
LY6E Q16553 lymphocyte antigen 6 family member E 0.32 0.563 0.808
NEFL P07196 neurofilament light 0.488 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
PLEKHG4 Q58EX7 pleckstrin homology and RhoGEF domain containing G4 1.1E-16 0.769 0.154
PPP2R2B Q00005 protein phosphatase 2 regulatory subunit Bbeta Enzyme 0.98 0.601 0.577
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SPTBN2 O15020 spectrin beta, non-erythrocytic 2 9.9E-05 0.619 0.731
TBP P20226 TATA-box binding protein Transcription factor 1.5E-02 0.552 0.846
TMEM240 Q5SV17 transmembrane protein 240 0.23 0.760 0.231
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
TTBK2 Q6IQ55 tau tubulin kinase 2 Kinase 1.00 0.682 0.423
TTPA P49638 alpha tocopherol transfer protein Transporter 1.4E-03 0.612 0.577