| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
| SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
| MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
| GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
| VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
| PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
| FMR1 | Q06787 | FMRP translational regulator 1 | Nucleic acid binding | 0.65 | 0.473 | 0.769 |
| FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
| C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
| TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
| TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
| TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
| CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
| PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
| SPAST | Q9UBP0 | spastin | Cellular structure | 1.00 | 0.579 | 0.577 |
| FTL | P02792 | ferritin light chain | Storage | 1.7E-09 | 0.559 | 0.692 |
| TYROBP | O43914 | transmembrane immune signaling adaptor TYROBP | 0.20 | 0.573 | 0.769 | |
| TMEM106B | Q9NUM4 | transmembrane protein 106B | 0.33 | 0.590 | 0.462 | |
| TOMM40 | O96008 | translocase of outer mitochondrial membrane 40 | Transporter | 0.99 | 0.590 | 0.538 |
| CHCHD10 | Q8WYQ3 | coiled-coil-helix-coiled-coil-helix domain containing 10 | 5.4E-06 | 0.623 | 0.462 | |
| VPS13A | Q96RL7 | vacuolar protein sorting 13 homolog A | 9.3E-22 | 0.650 | 0.577 | |
| SORL1 | Q92673 | sortilin related receptor 1 | Transporter | 7.7E-11 | 0.582 | 0.692 |
| ABCA7 | Q8IZY2 | ATP binding cassette subfamily A member 7 | Transporter | 2.1E-55 | 0.644 | 0.577 |