Disease: Senile Plaques
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APBB1 O00213 amyloid beta precursor protein binding family B member 1 0.97 0.722 0.346
APBA2 Q99767 amyloid beta precursor protein binding family A member 2 Transporter 0.74 0.700 0.385
HOOK1 Q9UJC3 hook microtubule tethering protein 1 Enzyme modulator 3.9E-08 0.716 0.462
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
IDE P14735 insulin degrading enzyme Enzyme 6.6E-03 0.604 0.577
SNCB Q16143 synuclein beta Transporter 6.8E-02 0.619 0.577
SRPX P78539 sushi repeat containing protein X-linked 3.1E-03 0.653 0.577
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
NRGN Q92686 neurogranin 0.48 0.608 0.615
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
HTT P42858 huntingtin 1.00 0.548 0.654
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
MX1 P20591 MX dynamin like GTPase 1 Enzyme modulator 3.4E-18 0.599 0.731
TSHZ1 Q6ZSZ6 teashirt zinc finger homeobox 1 Transcription factor 1.00 0.569 0.731
OGA O60502 O-GlcNAcase 0.97 0.534 0.731
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
EIF2AK2 P19525 eukaryotic translation initiation factor 2 alpha kinase 2 Kinase 1.8E-02 0.538 0.769
FHL5 Q5TD97 four and a half LIM domains 5 Transcription factor 4.8E-10 0.530 0.769
ACOT7 O00154 acyl-CoA thioesterase 7 Enzyme 0.76 0.531 0.769
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769