Disease: Congenital Heart Defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
CAV3 P56539 caveolin 3 Enzyme modulator 5.5E-03 0.564 0.692
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
GJA5 P36382 gap junction protein alpha 5 Cell-cell junction 1.8E-02 0.575 0.577
HAND2 P61296 heart and neural crest derivatives expressed 2 0.40 0.612 0.500
HCN4 Q9Y3Q4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 Ion channel 1.00 0.617 0.269
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
MYH6 P13533 myosin heavy chain 6 1.6E-32 0.581 0.615
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692
NKX2-5 P52952 NK2 homeobox 5 Transcription factor 0.95 0.533 0.692
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808
PITX2 Q99697 paired like homeodomain 2 0.98 0.489 0.808
PKD1L1 Q8TDX9 polycystin 1 like 1, transient receptor potential channel interacting Ion channel 1.1E-40 0.729 0.231
PLN P26678 phospholamban 0.45 0.595 0.577
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RYR2 Q92736 ryanodine receptor 2 Ion channel 1.00 0.539 0.615
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SLIT3 O75094 slit guidance ligand 3 0.75 0.623 0.615
SSPN Q14714 sarcospan 4.0E-02 0.716 0.462
TBX3 O15119 T-box transcription factor 3 Transcription factor 0.99 0.525 0.769
TBX5 Q99593 T-box transcription factor 5 Transcription factor 1.00 0.528 0.769