Disease: Aortic coarctation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
FOXC1 Q12948 forkhead box C1 Transcription factor 0.95 0.483 0.846
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
GATA6 Q92908 GATA binding protein 6 1.00 0.478 0.808
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
KDM6A O15550 lysine demethylase 6A Epigenetic regulator 1.00 0.498 0.769
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808
MCTP2 Q6DN12 multiple C2 and transmembrane domain containing 2 6.0E-52 0.623 0.577
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
NR2F2 P24468 nuclear receptor subfamily 2 group F member 2 Nuclear receptor 0.99 0.575 0.692
RAP1A P62834 RAP1A, member of RAS oncogene family Enzyme modulator 0.62 0.502 0.808
RAP1B P61224 RAP1B, member of RAS oncogene family Enzyme modulator 0.91 0.565 0.769
RPS19 P39019 ribosomal protein S19 Nucleic acid binding 0.92 0.480 0.846
STRA6 Q9BX79 signaling receptor and transporter of retinol STRA6 1.5E-10 0.597 0.731
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
TBX5 Q99593 T-box transcription factor 5 Transcription factor 1.00 0.528 0.769
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808