Disease: Hereditary hemochromatosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
DMRT1 Q9Y5R6 doublesex and mab-3 related transcription factor 1 0.74 0.559 0.654
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
FGF10 O15520 fibroblast growth factor 10 Signaling 0.94 0.530 0.692
FGFRL1 Q8N441 fibroblast growth factor receptor like 1 Enzyme 1.2E-02 0.588 0.615
FOXC2 Q99958 forkhead box C2 Transcription factor 0.13 0.515 0.731
FOXF1 Q12946 forkhead box F1 0.96 0.540 0.692
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
GATA6 Q92908 GATA binding protein 6 1.00 0.478 0.808
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
GPC3 P51654 glypican 3 1.00 0.466 0.808
KIAA0586 Q9BVV6 KIAA0586 5.1E-16 0.565 0.731
KIF7 Q2M1P5 kinesin family member 7 2.3E-22 0.528 0.731
LEP P41159 leptin 0.46 0.349 0.846
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NR4A3 Q92570 nuclear receptor subfamily 4 group A member 3 Nuclear receptor 0.91 0.502 0.808
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
SLC11A2 P49281 solute carrier family 11 member 2 Transporter 6.7E-03 0.566 0.769
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769