Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
MIR34B microRNA 34b 0.509 0.808
PPP2R1A P30153 protein phosphatase 2 scaffold subunit Aalpha Enzyme 0.98 0.588 0.577
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CCNE1 P24864 cyclin E1 Enzyme modulator 0.97 0.538 0.731
PTPA Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 0.99 0.480 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962