Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MIR200C microRNA 200c 0.486 0.846
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTPA Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 0.99 0.480 0.846
RPS19 P39019 ribosomal protein S19 Nucleic acid binding 0.92 0.480 0.846
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
YY1 P25490 YY1 transcription factor Transcription factor 0.99 0.481 0.808