Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MIR200C | microRNA 200c | 0.486 | 0.846 | |||
MKI67 | P46013 | marker of proliferation Ki-67 | 1.3E-28 | 0.431 | 0.808 | |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PPP2R1A | P30153 | protein phosphatase 2 scaffold subunit Aalpha | Enzyme | 0.98 | 0.588 | 0.577 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PTPA | Q15257 | protein phosphatase 2 phosphatase activator | Enzyme modulator | 0.99 | 0.480 | 0.846 |
TOP1 | P11387 | DNA topoisomerase I | Enzyme | 1.00 | 0.542 | 0.692 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
ZEB1 | P37275 | zinc finger E-box binding homeobox 1 | Transcription factor | 0.97 | 0.442 | 0.808 |