Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CCNE1 P24864 cyclin E1 Enzyme modulator 0.97 0.538 0.731
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
MIR34B microRNA 34b 0.509 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PPP2R1A P30153 protein phosphatase 2 scaffold subunit Aalpha Enzyme 0.98 0.588 0.577
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTPA Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 0.99 0.480 0.846
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962