Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
CTSB | P07858 | cathepsin B | Enzyme | 5.9E-11 | 0.457 | 0.846 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
EPHA2 | P29317 | EPH receptor A2 | Kinase | 1.1E-05 | 0.501 | 0.731 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ERBB3 | P21860 | erb-b2 receptor tyrosine kinase 3 | Kinase | 1.7E-15 | 0.448 | 0.808 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
FLT1 | P17948 | fms related receptor tyrosine kinase 1 | Kinase | 1.00 | 0.419 | 0.846 |
GJA1 | P17302 | gap junction protein alpha 1 | Cell-cell junction | 0.16 | 0.393 | 0.885 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | |
KLK3 | P07288 | kallikrein related peptidase 3 | Enzyme | 4.4E-06 | 0.443 | 0.885 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MIR21 | microRNA 21 | 0.363 | 0.846 | |||
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
TOP1 | P11387 | DNA topoisomerase I | Enzyme | 1.00 | 0.542 | 0.692 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TXNIP | Q9H3M7 | thioredoxin interacting protein | 0.16 | 0.490 | 0.731 |