Disease: Optic Atrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MFSD8 Q8NHS3 major facilitator superfamily domain containing 8 2.5E-12 0.682 0.231
TUBGCP6 Q96RT7 tubulin gamma complex associated protein 6 Cellular structure 2.6E-31 0.695 0.308
NDUFA11 Q86Y39 NADH:ubiquinone oxidoreductase subunit A11 1.8E-02 0.705 0.308
AUH Q13825 AU RNA binding methylglutaconyl-CoA hydratase Enzyme 8.0E-06 0.686 0.346
AP3B2 Q13367 adaptor related protein complex 3 subunit beta 2 Transporter 0.77 0.691 0.346
NECAP1 Q8NC96 NECAP endocytosis associated 1 0.13 0.691 0.346
NDUFA9 Q16795 NADH:ubiquinone oxidoreductase subunit A9 Enzyme 4.8E-03 0.653 0.385
SERAC1 Q96JX3 serine active site containing 1 3.9E-06 0.686 0.385
STAMBP O95630 STAM binding protein Enzyme 5.4E-05 0.653 0.423
WDR45 Q9Y484 WD repeat domain 45 0.99 0.647 0.423
TRAK1 Q9UPV9 trafficking kinesin protein 1 Transporter 3.7E-04 0.674 0.423
SZT2 Q5T011 SZT2 subunit of KICSTOR complex 2.3E-14 0.670 0.423
PARS2 Q7L3T8 prolyl-tRNA synthetase 2, mitochondrial Enzyme 4.1E-03 0.644 0.423
SEPSECS Q9HD40 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 1.6E-08 0.656 0.423
ARV1 Q9H2C2 ARV1 homolog, fatty acid homeostasis modulator 3.6E-06 0.691 0.423
KCTD7 Q96MP8 potassium channel tetramerization domain containing 7 Enzyme modulator 6.3E-04 0.650 0.423
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
KCNB1 Q14721 potassium voltage-gated channel subfamily B member 1 Ion channel 1.00 0.650 0.462
ZNF592 Q92610 zinc finger protein 592 1.00 0.700 0.462
EMC1 Q8N766 ER membrane protein complex subunit 1 6.7E-26 0.700 0.462
ACTL6B O94805 actin like 6B Cellular structure 2.8E-04 0.656 0.462
TOE1 Q96GM8 target of EGR1, exonuclease Nucleic acid binding 6.0E-16 0.682 0.462
DGUOK Q16854 deoxyguanosine kinase Kinase 3.7E-07 0.593 0.500
GABRB2 P47870 gamma-aminobutyric acid type A receptor subunit beta2 Ion channel 0.85 0.619 0.500