Disease: Acidosis, Lactic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TK2 O00142 thymidine kinase 2 Kinase 3.9E-07 0.585 0.615
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
COQ9 O75208 coenzyme Q9 5.5E-06 0.700 0.423
NDUFS2 O75306 NADH:ubiquinone oxidoreductase core subunit S2 Enzyme 1.4E-03 0.601 0.654
FARS2 O95363 phenylalanyl-tRNA synthetase 2, mitochondrial Enzyme 9.3E-09 0.615 0.731
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
ALB P02768 albumin Transporter 0.64 0.317 0.962
PCCA P05165 propionyl-CoA carboxylase subunit alpha Enzyme 3.1E-15 0.682 0.538
PCCB P05166 propionyl-CoA carboxylase subunit beta Enzyme 1.5E-08 0.695 0.577
IL6 P05231 interleukin 6 0.32 0.248 0.962
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846
PDHA1 P08559 pyruvate dehydrogenase E1 subunit alpha 1 0.99 0.581 0.538
HSPA5 P11021 heat shock protein family A (Hsp70) member 5 0.77 0.434 0.885
NDUFV2 P19404 NADH:ubiquinone oxidoreductase core subunit V2 5.6E-03 0.610 0.500
NDUFS1 P28331 NADH:ubiquinone oxidoreductase core subunit S1 Enzyme 6.6E-11 0.595 0.692
PCK1 P35558 phosphoenolpyruvate carboxykinase 1 Kinase 8.7E-15 0.608 0.538
NDUFV1 P49821 NADH:ubiquinone oxidoreductase core subunit V1 6.4E-11 0.617 0.538
SUCLG1 P53597 succinate-CoA ligase GDP/ADP-forming subunit alpha 4.8E-04 0.666 0.423
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
EXOSC9 Q06265 exosome component 9 Enzyme 1.8E-11 0.705 0.423
DGUOK Q16854 deoxyguanosine kinase Kinase 3.7E-07 0.593 0.500
TIMM50 Q3ZCQ8 translocase of inner mitochondrial membrane 50 1.8E-03 0.678 0.500
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
LYRM7 Q5U5X0 LYR motif containing 7 2.2E-02 0.716 0.346