Disease: Mental deterioration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692
SPON1 Q9HCB6 spondin 1 Extracellular structure 0.705 0.385
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808
SLC1A2 P43004 solute carrier family 1 member 2 Transporter 0.71 0.511 0.731
SLC17A5 Q9NRA2 solute carrier family 17 member 5 Transporter 6.9E-10 0.491 0.808
SLC13A5 Q86YT5 solute carrier family 13 member 5 Transporter 5.1E-04 0.608 0.577
SCN9A Q15858 sodium voltage-gated channel alpha subunit 9 Ion channel 4.8E-19 0.543 0.615
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SCN3A Q9NY46 sodium voltage-gated channel alpha subunit 3 Ion channel 1.00 0.617 0.538
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
RNF216 Q9NWF9 ring finger protein 216 2.3E-06 0.670 0.615
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PQBP1 O60828 polyglutamine binding protein 1 Transcription factor 0.79 0.570 0.654
PPP3CA Q08209 protein phosphatase 3 catalytic subunit alpha 1.00 0.568 0.769
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538
PARS2 Q7L3T8 prolyl-tRNA synthetase 2, mitochondrial Enzyme 4.1E-03 0.644 0.423
P4HB P07237 prolyl 4-hydroxylase subunit beta 1.00 0.488 0.808
NUS1 Q96E22 NUS1 dehydrodolichyl diphosphate synthase subunit 0.98 0.619 0.615
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
NRGN Q92686 neurogranin 0.48 0.608 0.615
NEFL P07196 neurofilament light 0.488 0.769