Disease: Mental deterioration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TBC1D24 Q9ULP9 TBC1 domain family member 24 Enzyme modulator 1.3E-08 0.530 0.808
CLN5 O75503 CLN5 intracellular trafficking protein 1.7E-08 0.705 0.269
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
CLN3 Q13286 CLN3 lysosomal/endosomal transmembrane protein, battenin Transporter 1.3E-07 0.572 0.692
CD33 P20138 CD33 molecule Receptor 5.7E-07 0.524 0.769
TPP1 O14773 tripeptidyl peptidase 1 Enzyme 6.3E-07 0.551 0.808
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
RNF216 Q9NWF9 ring finger protein 216 2.3E-06 0.670 0.615
ARV1 Q9H2C2 ARV1 homolog, fatty acid homeostasis modulator 3.6E-06 0.691 0.423
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CLU P10909 clusterin 7.8E-05 0.426 0.885
XPA P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 7.9E-05 0.520 0.846
CLN6 Q9NWW5 CLN6 transmembrane ER protein 1.0E-04 0.670 0.231
TANGO2 Q6ICL3 transport and golgi organization 2 homolog 1.5E-04 0.666 0.615
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769
UBA5 Q9GZZ9 ubiquitin like modifier activating enzyme 5 Enzyme 2.5E-04 0.582 0.731
ACTL6B O94805 actin like 6B Cellular structure 2.8E-04 0.656 0.462
TRAK1 Q9UPV9 trafficking kinesin protein 1 Transporter 3.7E-04 0.674 0.423
SLC13A5 Q86YT5 solute carrier family 13 member 5 Transporter 5.1E-04 0.608 0.577
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
NDUFS2 O75306 NADH:ubiquinone oxidoreductase core subunit S2 Enzyme 1.4E-03 0.601 0.654
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962