Disease: Alcohol Use Disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACACA Q13085 acetyl-CoA carboxylase alpha 1.00 0.480 0.846
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BMS1 Q14692 BMS1 ribosome biogenesis factor 1.8E-04 0.499 0.846
CCKAR P32238 cholecystokinin A receptor G-protein coupled receptor 4.0E-03 0.615 0.500
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
LEP P41159 leptin 0.46 0.349 0.846
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
NPY2R P49146 neuropeptide Y receptor Y2 G-protein coupled receptor 3.6E-02 0.612 0.577
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
PNOC Q13519 prepronociceptin Signaling 1.5E-02 0.603 0.577
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SORCS2 Q96PQ0 sortilin related VPS10 domain containing receptor 2 Transporter 3.2E-03 0.743 0.346
TMEM97 Q5BJF2 transmembrane protein 97 Enzyme 3.1E-04 0.604 0.615