Disease: Nicotine Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CHRM2 P08172 cholinergic receptor muscarinic 2 G-protein coupled receptor 0.18 0.585 0.615
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CSMD1 Q96PZ7 CUB and Sushi multiple domains 1 1.00 0.610 0.500
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
FRMD4A Q9P2Q2 FERM domain containing 4A 1.00 0.650 0.538
GRIA4 P48058 glutamate ionotropic receptor AMPA type subunit 4 Ion channel 1.8E-02 0.631 0.615
GRIK2 Q13002 glutamate ionotropic receptor kainate type subunit 2 Ion channel 1.00 0.561 0.769
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
GRM7 Q14831 glutamate metabotropic receptor 7 G-protein coupled receptor 1.00 0.628 0.538
NRXN3 Q9HDB5 Q9Y4C0 neurexin 3 1.00 0.656 0.615
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808