Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
ALB | P02768 | albumin | Transporter | 0.64 | 0.317 | 0.962 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
MUC1 | P15941 | mucin 1, cell surface associated | 1.9E-02 | 0.384 | 0.885 | |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
PROM1 | O43490 | prominin 1 | Transporter | 1.9E-22 | 0.410 | 0.846 |
SOX9 | P48436 | SRY-box transcription factor 9 | 1.00 | 0.419 | 0.846 | |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
CD163 | Q86VB7 | CD163 molecule | Enzyme | 8.3E-04 | 0.427 | 0.846 |
MKI67 | P46013 | marker of proliferation Ki-67 | 1.3E-28 | 0.431 | 0.808 | |
ERCC1 | P07992 | ERCC excision repair 1, endonuclease non-catalytic subunit | Enzyme | 1.6E-07 | 0.445 | 0.846 |
MIB1 | Q86YT6 | mindbomb E3 ubiquitin protein ligase 1 | Enzyme | 3.4E-88 | 0.438 | 0.769 |
TP73 | O15350 | tumor protein p73 | Transcription factor | 1.00 | 0.449 | 0.808 |
CIB1 | Q99828 | calcium and integrin binding 1 | 3.3E-04 | 0.458 | 0.769 |