Source: BEFREE ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923