Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
ATP6AP2 O75787 ATPase H+ transporting accessory protein 2 Receptor 0.87 0.525 0.769
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
STUB1 Q9UNE7 STIP1 homology and U-box containing protein 1 1.9E-02 0.544 0.692
HTT P42858 huntingtin 1.00 0.548 0.654
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
ABCD1 P33897 ATP binding cassette subfamily D member 1 Transporter 1.00 0.563 0.731
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692
FA2H Q7L5A8 fatty acid 2-hydroxylase Enzyme 0.15 0.573 0.654
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
RAB18 Q9NP72 RAB18, member RAS oncogene family 0.91 0.582 0.692
SPART Q8N0X7 spartin 3.0E-07 0.588 0.654
ADGRG1 Q9Y653 adhesion G protein-coupled receptor G1 G-protein coupled receptor 5.3E-10 0.590 0.654
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
ATL1 Q8WXF7 atlastin GTPase 1 Enzyme modulator 0.98 0.593 0.654
SLC52A3 Q9NQ40 solute carrier family 52 member 3 Transporter 1.9E-02 0.610 0.654
PIGT Q969N2 phosphatidylinositol glycan anchor biosynthesis class T 7.3E-10 0.633 0.615
POU3F4 P49335 POU class 3 homeobox 4 0.57 0.633 0.654
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
ERLIN2 O94905 ER lipid raft associated 2 6.7E-04 0.647 0.500