Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
B2M | P61769 | beta-2-microglobulin | Immune response | 0.56 | 0.447 | 0.846 |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
GATA6 | Q92908 | GATA binding protein 6 | 1.00 | 0.478 | 0.808 | |
TYMP | P19971 | thymidine phosphorylase | Enzyme | 1.2E-04 | 0.495 | 0.769 |
DAXX | Q9UER7 | death domain associated protein | 9.9E-02 | 0.544 | 0.692 | |
G6PC | P35575 | glucose-6-phosphatase catalytic subunit | 1.8E-05 | 0.560 | 0.692 | |
COG4 | Q9H9E3 | component of oligomeric golgi complex 4 | 4.0E-09 | 0.631 | 0.615 | |
PALLD | Q8WX93 | palladin, cytoskeletal associated protein | 5.3E-06 | 0.628 | 0.615 | |
ACSF3 | Q4G176 | acyl-CoA synthetase family member 3 | Enzyme | 2.3E-26 | 0.743 | 0.308 |