Disease: Macrocephaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808
AP1S2 P56377 adaptor related protein complex 1 subunit sigma 2 Transporter 0.87 0.631 0.615
APC2 O95996 APC regulator of WNT signaling pathway 2 1.00 0.582 0.654
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CAMK2G Q13555 calcium/calmodulin dependent protein kinase II gamma Kinase 1.00 0.670 0.462
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
CNKSR2 Q8WXI2 connector enhancer of kinase suppressor of Ras 2 1.00 0.628 0.538
CUL4B Q13620 cullin 4B Enzyme 1.00 0.556 0.769
DIS3L2 Q8IYB7 DIS3 like 3'-5' exoribonuclease 2 0.94 0.647 0.500
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
ETFA P13804 electron transfer flavoprotein subunit alpha Enzyme 2.9E-03 0.508 0.731
ETFB P38117 electron transfer flavoprotein subunit beta Enzyme 1.7E-02 0.711 0.538
ETFDH Q16134 electron transfer flavoprotein dehydrogenase Enzyme 2.8E-13 0.678 0.462
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692
FRMPD4 Q14CM0 FERM and PDZ domain containing 4 1.00 0.674 0.423
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
HSD17B4 P51659 hydroxysteroid 17-beta dehydrogenase 4 2.4E-10 0.546 0.654
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769
IGBP1 P78318 immunoglobulin binding protein 1 Immune response 0.98 0.641 0.692