Disease: Clinodactyly of the 5th finger
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
A2ML1 A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 1.6E-34 0.590 0.692
ANKRD11 Q6UB99 ankyrin repeat domain 11 1.00 0.556 0.808
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BUB1 O43683 BUB1 mitotic checkpoint serine/threonine kinase Kinase 4.9E-09 0.528 0.731
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
BUB3 O43684 BUB3 mitotic checkpoint protein Nucleic acid binding 0.81 0.588 0.615
CENPJ Q9HC77 centromere protein J Enzyme 2.1E-27 0.546 0.846
CEP57 Q86XR8 centrosomal protein 57 7.3E-02 0.615 0.615
CLIP2 Q9UDT6 CAP-Gly domain containing linker protein 2 Cellular structure 1.00 0.529 0.808
CUL4B Q13620 cullin 4B Enzyme 1.00 0.556 0.769
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
EBF3 Q9H4W6 EBF transcription factor 3 1.00 0.595 0.731
ELN P15502 elastin 2.1E-14 0.415 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GMNN O75496 geminin DNA replication inhibitor 0.11 0.554 0.808
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808
GTF2IRD1 Q9UHL9 GTF2I repeat domain containing 1 0.90 0.522 0.769
HIC1 Q14526 HIC ZBTB transcriptional repressor 1 Transcription factor 0.13 0.522 0.615
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769
IFT52 Q9Y366 intraflagellar transport 52 2.0E-06 0.653 0.538
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731