Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
SOX2 | P48431 | SRY-box transcription factor 2 | Transcription factor | 0.71 | 0.405 | 0.808 |
BMP4 | P12644 | bone morphogenetic protein 4 | Signaling | 0.96 | 0.422 | 0.808 |
CHD7 | Q9P2D1 | chromodomain helicase DNA binding protein 7 | 1.00 | 0.441 | 0.846 | |
NOTCH3 | Q9UM47 | notch receptor 3 | 0.41 | 0.435 | 0.808 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
NOTCH2 | Q04721 | notch receptor 2 | 1.00 | 0.441 | 0.808 | |
YAP1 | P46937 | Yes associated protein 1 | Enzyme modulator | 1.00 | 0.432 | 0.808 |
GLI2 | P10070 | GLI family zinc finger 2 | 0.97 | 0.446 | 0.846 | |
PAX6 | P26367 | paired box 6 | 1.00 | 0.450 | 0.769 | |
MMP14 | P50281 | matrix metallopeptidase 14 | Enzyme | 1.00 | 0.447 | 0.769 |
RB1 | P06400 | RB transcriptional corepressor 1 | Nucleic acid binding | 1.00 | 0.444 | 0.885 |
FLI1 | Q01543 | Fli-1 proto-oncogene, ETS transcription factor | Transcription factor | 0.99 | 0.468 | 0.692 |
BCOR | Q6W2J9 | BCL6 corepressor | 1.00 | 0.471 | 0.808 |